TB500 10mg

£34.99 inc. VAT

In stock

Format

Format *
- Standard Vial
- Pre-filled Cartridge (without pen) + £15.00
- Disposable Pen inc.. Pre-filled Cartridge + £25.00
- Reusable Pen inc. Pre-filled Cartridge + £35.00
Shipping Upgrade *

Cold-Chain Logistics Upgrade – Temperature-Controlled Shipping + £14.99 inc. VAT

*

⚠️ COLD-CHAIN LOGISTICS: We utilise specialized Cold-Chain Logistics for these pre-mixed solutions; therefore, Express Shipping is mandatory for Cartridges and Pen systems to ensure maximum product stability and integrity.

*

Reusable pens are temporarily out of stock.

Product total

Options total

Grand total

**For bulk orders (10 or over), please email us.

Add to wishlist

TB-500 (10mg) — Research Compound TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, which is found in high concentrations in blood platelets and wound fluid. It is primarily studied for its role in actin sequestration, a process critical for cell migration and tissue repair. Researchers investigate TB-500 for its ability to promote angiogenesis (new blood vessel formation) and its systemic impact on the recovery of contractile and connective tissues following injury. Findings from early-stage clinical trials have reported:

Accelerated migration of keratinocytes and endothelial cells observed in wound healing models
Enhanced rates of collagen deposition and tissue remodeling reported in tendon and ligament research
Reductions in localized inflammatory signaling markers noted following acute administration
Improved recovery of muscle fiber functionality and reduced scar tissue formation observed in-vivo

Researchers utilize TB-500 to study the biological pathways of regenerative medicine and structural tissue repair. Because of its low molecular weight, it is investigated for its ability to travel through tissues and target sites of injury systemically. This makes it an essential compound for research into chronic wound management, sports-related injuries, and the cellular mechanisms of structural recovery. Available Formats: This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system. Used solely for in vitro experiments and cannot be:

Used in clinical trials involving humans
Administered to humans as part of an experiment or investigation
Supplied to another party for human investigational use

References

Thymosin β4 promotes endothelial cell migration and angiogenesis This foundational study investigated Thymosin Beta-4 and demonstrated its role in endothelial cell migration, wound repair, and angiogenic signalling pathways. Source Link: Available here Thymosin Beta-4: a multifunctional regenerative peptide This review summarises the biological activities of Thymosin Beta-4, including tissue repair, inflammation regulation, and cellular migration research. Source Link: Available here Thymosin β4 and tissue regeneration research Researchers reviewed the regenerative properties of Thymosin Beta-4 across cardiac, dermal, and musculoskeletal experimental models. Source Link: Available here

Certificate of Analysis (COA): Available here

TB500 10mg FAQs

What is TB 500?

TB 500 is a synthetic version of the naturally occurring substance in the thymus gland.

How to store TB 500?

For long-term storage, unopened TB-500 is recommended to be stored at -20°C. However, once the vial has been opened, it’s best to refrigerate at 2–8°C.

This helps protect the vial's rubber stopper from potential damage caused by freezing and thawing. It also reduces confusion between a vial that has simply had its tamper-evident cap removed and one that has been reconstituted.

Unopened, these peptides have a shelf life of 2 years. Once opened, they stay stable for 28 days at 2-8°C in sterile aqueous solution.

Once TB-500 has been reconstituted (liquid has been added), it must not be frozen. Reconstituted product should always be stored refrigerated at 2–8°C.

What are the known safety considerations from research studies?

Published research highlights general safety observations in controlled models, although data is limited and not indicative of clinical safety or efficacy.

What is TB 500 used for?

As a synthetic research peptide, it is used solely to study biological processes such as cell migration, actin regulation and tissue modelling pathways in laboratory or preclinical models. Researchers investigate how this fragment interacts with the cytoskeleton, influences cellular organisation or participates in wound healing-related mechanisms in a controlled experimental environment, not in clinical or therapeutic contexts.

What are BPC157 and TB 500?

BPC-157 and TB-500 are studied peptides investigated exclusively in preclinical experimental research settings. BPC-157 is a synthetic fragment derived from a protein found in the gastric tissue, and researchers use it to explore cellular signalling, angiogenesis pathways and tissue modelling processes in controlled models.

TB 500 is a synthetic analogue based on a region of Thymosin eta 4, which is studied for its role in actin regulation, cell migration and cytoskeletal organisation. In research settings, these peptides are tools for examining fundamental biological mechanisms, not for clinical or therapeutic use.

What is a BPC 157 TB 500 blend?

A BPC- 157 and TB-500 blend is an experimental combination of two synthetic peptides frequently explored for their potential to accelerate tissue repair. When combined, the two compounds may offer complementary benefits, although further research is required. TB-500 may provide broad, body-wide support, whilst BPC-157 focuses on specific injuries to promote focused healing.

How is TB-500 studied in scientific research?

It is studied primarily as a synthetic, fragmented derivative of the naturally occurring Thymosin Beta-4 protein. It consists of a specific 43-amino-acid chain sequence and is primarily evaluated for its role in cellular migration, angiogenesis, and tissue repair.

Weight	10 kg

IDENTIFICATION
Product Name	TB-500 10 mg
Catalogue Number	RP-TB500-01
CAS Number	77591-33-4
Molecular Weight (g/mol)	4963.5 g/mol
Molecular Formula	C212H350N56O78S
Peptide Sequence	Thymosin beta-4 fragment (43 amino acids)
PHYSICAL AND CHEMICAL PROPERTIES
Active Ingredient	TB-500
Appearance	White to off-white lyophilised powder
Melting Point	Not applicable (decomposes before melting)
ANALYTICAL AND QUALITY CONTROL
Mass Spectrum	Conforms to specification
Structural Confirmation	Consistent with theoretical structure / sequence
RESEARCH USE AND SAFETY
Caution	Handle using appropriate PPE and in compliance with relevant laboratory safety standards.
Intended Use	For laboratory research use only. Not for human or veterinary use.
Hazard Classification	Not classified as hazardous under GHS for research quantities
STORAGE, HANDLING AND STABILITY
Storage Temperature, Opened	-20 °C, minimise freeze–thaw cycles
Storage Temperature, Unopened	-20 °C recommended for long-term storage
Shelf Life	2 years unopened under recommended conditions
Reconstitution Stability	Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions

Certificate of Analysis – TB-500 (99% Purity Verified)

COMPOUND IDENTIFICATION
Product Name	TB-500 (10mg)
Batch / Reference ID	TB100124
Sample Form	White powder in glass vial
ANALYTICAL RESULTS
Chemical Purity	99% (Verified)
Measured Content	10.80 mg (± 0.05 mg)
Test Method	HPLC (High-Performance Liquid Chromatography)
LABORATORY TESTING INFORMATION
Analysis Period	03 Mar 2026 – 09 Mar 2026
Laboratory Order #	100012952
QUALITY ASSURANCE
Quality Testing Standards	All River Peptides products undergo batch-level laboratory analysis to verify compound identity and confirm purity levels. Learn more on our Quality Testing & Purity Verification page.