5-Amino-1MQ – 10mg Spray
5-Amino-1MQ is a small molecule that functions as a selective, membrane-permeable inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). This enzyme plays a critical role in cellular energy metabolism by regulating the levels of nicotinamide adenine dinucleotide (NAD+). In research settings, 5-Amino-1MQ is studied for its ability to prevent the depletion of NAD+ and its consequent impact on metabolic efficiency and muscle cell regeneration.
Findings from early-stage clinical trials have reported:
- Reductions in white adipose tissue mass of approximately 30% observed in experimental rodent models
- Increases in intracellular NAD+ levels and ATP production reported in muscle cell cultures
- Improved contractile force and enhanced recovery of injured muscle fibres noted in-vivo
- Alterations in the expression of genes associated with lipid metabolism observed in research studies
Researchers study 5-Amino-1MQ to better understand the role of the NNMT pathway in metabolic disorders and muscle wasting. Its ability to influence cellular energy homeostasis without affecting systemic neurotransmitter levels makes it a unique tool for investigating metabolic health at the cellular level. This compound is essential for research into the biological mechanisms of ageing and the potential for pharmacological intervention in energy-intensive tissues.
Available Formats:
This compound is available in a 9ml premixed spray bottle, providing a stable solution for precise administration in research settings.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
Certificate of Analysis (COA): Available here
| IDENTIFICATION | |
| Product Name | 5-Amino-1MQ (iodide) 10 mg |
| Catalogue Number | RP-5AMINO1MQ-01 |
| CAS Number | 42464-96-0 |
| Molecular Weight (g/mol) | 286.11 g/mol |
| Molecular Formula | C10H11IN2 |
| Peptide Sequence | N/A (small molecule) |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | 5-Amino-1MQ (iodide) |
| Appearance | Yellow-orange to orange lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |
Certificate of Analysis – 5-Amino-1MQ (99% Purity Verified)
| COMPOUND IDENTIFICATION | |
| Product Name | 5-Amino-1MQ (10mg Spray) |
| Sample Name | 5-AMINO AM101218 |
| Batch / Reference ID | AM101218 |
| Laboratory Order Number | 100012243 |
| ANALYTICAL RESULTS | |
| Purity Result | 99% Chemical Purity |
| Measured Content | 10.83 mg |
| Measurement Error | ±0.05 mg |
| Test Method | HPLC Chromatography (Water / Acetonitrile + 0.1% TFA gradient) |
| LABORATORY TESTING INFORMATION | |
| Date Received | 27 January 2026 |
| Analysis Start Date | 06 February 2026 |
| Analysis Completion Date | 10 February 2026 |
| Sample Form | Orange powder in glass vial |
| QUALITY ASSURANCE | |
| Quality Testing Standards | All River Peptides products undergo batch-level laboratory analysis to confirm a minimum purity standard. Learn more on our Quality Testing & Purity Verification page. |
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