N-Acetyl Semax -10mg
N-Acetyl Semax is a synthetic N-acetylated analogue of Semax, a peptide derived from a fragment of the adrenocorticotropic hormone (ACTH 4-10). The addition of the acetyl group is studied for its ability to enhance the peptide’s stability, increase its resistance to enzymatic breakdown, and improve its ability to cross the blood-brain barrier. Researchers investigate this compound for its potent neurogenic effects, specifically its role in upregulating Brain-Derived Neurotrophic Factor (BDNF) and its potential to modulate the expression of genes involved in vascular health and immune response within the central nervous system.
Findings from early-stage clinical trials have reported:
- Significantly increased duration of biological activity and stability in plasma observed compared to the base peptide.
- Rapid upregulation of BDNF and Nerve Growth Factor (NGF) mRNA expression reported in hippocampal tissues.
- Enhanced cognitive markers related to sustained attention and information processing noted in experimental models.
- Observed protective effects against glutamate-induced excitotoxicity and oxidative stress in neuronal cell cultures.
Researchers study N-Acetyl Semax to explore the limits of neuroprotection and the biological mechanisms of cognitive enhancement. By analyzing its interaction with the melanocortin system and its impact on neuroplasticity, it serves as a specialized tool for investigating the recovery of neurological function after injury. This compound is a primary focus for research into advanced nootropic pathways and the preservation of neuronal integrity under metabolic stress.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
| IDENTIFICATION | |
| Product Name | N-Acetyl Semax 10 mg |
| Catalogue Number | RP-NASEMAX-10S |
| Batch Number | NX100403 |
| Peptide Sequence | Ac-Met-Glu-His-Phe-Pro-Gly-Pro |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | N-Acetyl Semax |
| Appearance | White powder in glass vial [cite: 207] |
| Form | 9ml premixed spray bottle (post-reconstitution) |
| ANALYTICAL AND QUALITY CONTROL | |
| Measured Content | 10.66 mg [cite: 209, 213] |
| Purity (HPLC) | 99% [cite: 209] |
| Structural Confirmation | Consistent with reference chromatogram (BioBasic 8 Thermo Scientific) [cite: 211, 213] |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and laboratory safety standards. |
| Intended Use | In vitro experiments only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | 2–8 °C for spray solution; avoid direct sunlight |
| Storage Temperature, Unopened | -20 °C recommended for long-term stability |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Spray formulation remains stable for up to 30 days when refrigerated |
Certificate of Analysis – N-Acetyl Semax (99% Purity Verified)
| COMPOUND IDENTIFICATION | |
| Product Name | N-Acetyl Semax (10mg Spray) |
| Batch / Reference ID | NX101217 |
| Sample Form | White powder in glass vial |
| ANALYTICAL RESULTS | |
| Chemical Purity | 99% (Verified) |
| Measured Content | 10.23mg (± 0.05mg) |
| Test Method | HPLC (High-Performance Liquid Chromatography) |
| LABORATORY TESTING INFORMATION | |
| Analysis Period | 06 Feb 2026 – 10 Feb 2026 |
| Laboratory Order # | 100012244 |
| QUALITY ASSURANCE | |
| Quality Testing Standards | All River Peptides products undergo batch-level laboratory analysis to verify compound identity and confirm purity levels. Learn more on our Quality Testing & Purity Verification page. |
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