CJC-1295 (No DAC) (5mg) — Research Compound
CJC-1295 (No DAC), also known as Tetrasubstituted GRF (1-29), is a synthetic peptide analogue of naturally occurring Growth Hormone Releasing Hormone (GHRH). It is designed to stimulate the pituitary gland to secrete growth hormone in a manner that mimics the natural physiological pulses of the body. In research settings, it is primarily used to investigate the regulation of the somatotropic axis and the downstream effects of transient increases in circulating growth hormone levels.
Findings from early-stage clinical trials have reported:
- Dose-dependent increases in mean plasma growth hormone concentrations observed following administration
- Significant elevations in circulating IGF-1 levels reported in healthy adult research cohorts
- Half-life extensions compared to native GHRH observed while maintaining a pulsatile release profile
- Observed improvements in slow-wave sleep duration and quality reported in experimental models
CJC-1295 (No DAC) is a critical research tool for studying the dynamics of the pituitary gland without the prolonged stimulation associated with long-acting analogues. Researchers use this compound to analyse the impact of acute growth hormone pulses on lipid metabolism and muscle protein accretion. Its rapid clearance and high receptor specificity make it ideal for experiments requiring precise control over the timing of hormonal signals.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
| IDENTIFICATION | |
| Product Name | CJC-1295 (No DAC) 5 mg |
| Catalogue Number | RP-CJC1295-NODAC-01 |
| CAS Number | 863288-34-0 |
| Molecular Weight (g/mol) | 3367.9 g/mol |
| Molecular Formula | C152H252N44O42 |
| Peptide Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | CJC-1295 (No DAC) |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure / sequence |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |
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