CJC-1295 without DAC

CJC-1295 (No DAC) (5mg) — Research Compound

CJC-1295 (No DAC), also known as Tetrasubstituted GRF (1-29), is a synthetic peptide analogue of naturally occurring Growth Hormone Releasing Hormone (GHRH). It is designed to stimulate the pituitary gland to secrete growth hormone in a manner that mimics the natural physiological pulses of the body. In research settings, it is primarily used to investigate the regulation of the somatotropic axis and the downstream effects of transient increases in circulating growth hormone levels.

Findings from early-stage clinical trials have reported:

• Dose-dependent increases in mean plasma growth hormone concentrations observed following administration
  
• Significant elevations in circulating IGF-1 levels reported in healthy adult research cohorts
  
• Half-life extensions compared to native GHRH observed while maintaining a pulsatile release profile
  
• Observed improvements in slow-wave sleep duration and quality reported in experimental models
  

CJC-1295 (No DAC) is a critical research tool for studying the dynamics of the pituitary gland without the prolonged stimulation associated with long-acting analogues. Researchers use this compound to analyse the impact of acute growth hormone pulses on lipid metabolism and muscle protein accretion. Its rapid clearance and high receptor specificity make it ideal for experiments requiring precise control over the timing of hormonal signals.

Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.

Used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use

References

Growth hormone-releasing hormone and its analogues in endocrine research
This review discusses GHRH analogues, including modified forms of CJC-1295, and their influence on growth hormone signalling pathways.
Source Link: Available here

Pharmacology of growth hormone-releasing hormone analogues
Researchers reviewed GHRH analogue activity and receptor-mediated signalling relevant to CJC-1295 without DAC research.
Source Link: Available here

Growth hormone regulation through GHRH receptor activation
This publication examines mechanisms involved in growth hormone release and endocrine pathway modulation.
Source Link: Available here

Certificate of Analysis (COA): Available here