P21 – 10mg Research Compound
£49.99 inc. VAT
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P21 (10mg) — Research Compound
P21 is a synthetic peptide designed to mimic the active region of natural brain growth factors. It is engineered with a special lipid-friendly structure to help it easily cross cellular barriers. In laboratory settings, P21 is primarily studied for its potential to encourage new brain cell growth, strengthen connections between neurons, and protect brain tissue against age-related decline.
Findings from early-stage research have reported:
- Stimulation of new brain cell creation observed in memory regions of rodent models
- Increases in synaptic connectivity and higher levels of key brain growth proteins
- Improved preservation of learning capacity and memory retention in models of cognitive decline
- Reductions in markers linked to neurodegenerative cellular damage
Researchers study P21 to better understand how brain cells repair themselves and form new neural pathways. Its ability to support brain plasticity and cellular renewal makes it a valuable research tool for exploring treatments for memory loss, neurodegenerative disorders, and overall brain health.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
References
P21-activated kinase and neuronal development research
This research examines P21-associated signalling pathways involved in neuronal development, neurite formation, synaptic organisation, and cellular plasticity. It provides mechanistic context relevant to studying synthetic neurogenic peptides designed to influence neuronal growth and connectivity. Available here
Neurotrophic factors, adult neurogenesis and neuronal plasticity
This review examines how neurotrophic signalling regulates the formation, survival, and integration of new neurons in the adult brain. It provides relevant scientific context for P21 research focused on neurogenesis, synaptic connectivity, and neuronal survival. Available here
Brain-derived neurotrophic factor signalling in synaptic plasticity and memory
This publication reviews BDNF-mediated signalling and its relationship with synaptic plasticity, neuronal connectivity, learning, and memory. These mechanisms are directly relevant to the neurotrophic pathways described for P21 research. Available here
| IDENTIFICATION | |
| Product Name | P21 10 mg |
| Catalogue Number | RP-P21-10 |
| Peptide Sequence | Ac-Asp-Gly-Gly-Leu-Aib-Val-NH2 (or equivalent mimetic sequence) |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | P21 (Synthetic neurogenic peptide mimetic) |
| Appearance | Lyophilised powder in glass vial |
| Form | Lyophilised powder / Available in disposable pen, reusable pen, or cartridge systems |
| ANALYTICAL AND QUALITY CONTROL | |
| Nominal Content | 10 mg |
| Purity (HPLC) | ≥ 98.0% |
| Structural Confirmation | Consistent with theoretical structure |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | Solely for in vitro laboratory research use. Not for human, clinical, or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended storage conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in sterile aqueous solution under aseptic conditions |

