VIP – 10mg Research Compound
£89.99 inc. VAT
In stock
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VIP – 10mg Research Compound
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide that functions as a potent vasodilator and immune modulator. It is found throughout the central and peripheral nervous systems, as well as the gastrointestinal tract. Researchers study VIP for its ability to regulate smooth muscle relaxation, influence circadian rhythms, and modulate the balance between pro-inflammatory and anti-inflammatory cytokines. It is a focal point for studies involving chronic inflammatory conditions, pulmonary health, and neuroprotection.
Findings from early-stage clinical trials have reported:
- Significant reductions in pulmonary arterial pressure observed in experimental models of lung disease.
- Marked decreases in systemic inflammatory markers, including TNF-α and IL-6, reported in-vivo.
- Improved survival rates and organ protection noted in experimental models of sepsis.
- Observed stabilization of the blood-brain barrier and neuroprotective effects reported in research cohorts.
Researchers utilize VIP to explore the neuroendocrine regulation of the immune system. By investigating its role as a “macrophage-deactivating factor,” it serves as a unique tool for studying the resolution of chronic inflammation. This compound is essential for research into the biological mechanisms of autoimmune regulation, respiratory health, and the preservation of vascular homeostasis.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
References
Immunomodulation of innate immune responses by vasoactive intestinal peptide
This review discusses VIP’s role in innate immune cell function and its relevance to inflammatory disease research, giving useful scientific context for VIP peptide pages.
Source Link: Available here
Vasoactive intestinal peptide as a neuropeptide with immune and inflammatory relevance
This paper reviews VIP as a peptide involved in both innate and adaptive immune regulation, supporting its relevance in neuroimmune and inflammatory pathway studies.
Source Link: Available here
A clinical approach for the use of the VIP axis in inflammatory and autoimmune disease research
This review summarises VIP-related pathways and potential clinical research relevance across inflammatory and autoimmune disease models.
Source Link: Available here
Certificate of Analysis (COA): Available here
| IDENTIFICATION | |
| Product Name | VIP 10 mg |
| Catalogue Number | RP-VIP-01 |
| CAS Number | 40077-57-4 |
| Molecular Weight (g/mol) | 3325 g/mol |
| Molecular Formula | C147H237N43O42 |
| Peptide Sequence | Vasoactive intestinal peptide (28 aa) |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | VIP |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure / sequence |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |
Certificate of Analysis – VIP (99% Purity Verified)
| COMPOUND IDENTIFICATION | |
| Product Name | VIP (Vasoactive Intestinal Peptide) |
| Batch / Reference ID | VI101109 |
| Sample Form | White powder in glass vial |
| ANALYTICAL RESULTS | |
| Chemical Purity | 99% (Verified) |
| Measured Content | 10.46 mg (± 0.05 mg) |
| Test Method | HPLC (High-Performance Liquid Chromatography) |
| LABORATORY TESTING INFORMATION | |
| Analysis Period | 06 Feb 2026 – 10 Feb 2026 |
| Laboratory Order # | 100012233 |
| QUALITY ASSURANCE | |
| Quality Testing Standards | All River Peptides products undergo batch-level laboratory analysis to verify compound identity and confirm purity levels. Learn more on our Quality Testing & Purity Verification page. |


