ARA-290 (10mg) — Research Compound
ARA-290 is a synthetic peptide derived from erythropoietin (EPO) and engineered to selectively activate tissue-protective signaling pathways without engaging the erythropoietic or hematopoietic effects of full-length EPO. In research settings, it is studied for its role in modulating inflammation, cellular stress responses, and tissue repair mechanisms.
Findings from early-stage clinical trials have reported:
- Significant reductions in neuropathic pain markers reported across experimental models.
- Improvements in nerve regeneration and repair observed in-vivo.
- Decreases in systemic inflammatory markers noted in research cohorts.
- Enhanced tissue recovery and protection against ischemic injury reported in metabolic studies.
Researchers study ARA-290 to explore the biological pathways involved in inflammation control, cellular resilience, and neuroprotective signaling, with particular interest in its potential relevance to neurological recovery and tissue protection.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
References
ARA290, a nonerythropoietic peptide engineered from erythropoietin
This study describes ARA290 as a synthetic peptide derived from erythropoietin that selectively activates the innate repair receptor while avoiding erythropoietic activity.
Source Link: Available here
ARA290 improves small nerve fibre pathology in sarcoidosis research
Researchers investigated ARA290 in models of neuropathic dysfunction and reported improvements in small fibre pathology and associated biomarkers.
Source Link: Available here
Innate repair receptor activation by ARA290
This publication explores the mechanism of ARA290 and its interaction with tissue-protective pathways involved in inflammation and cellular repair.
Source Link: Available here
| IDENTIFICATION | |
| Product Name | ARA-290 10 mg |
| Catalogue Number | RP-ARA290-01 |
| CAS Number | 902137-43-5 |
| Molecular Weight (g/mol) | ~899 g/mol |
| Molecular Formula | C40H63N13O12 |
| Peptide Sequence | Erythropoietin-derived peptide (ARA-290) |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | ARA-290 |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure / sequence |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |
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