MOTS-C (10mg) — Research Compound
MOTS-C is a mitochondrial-derived peptide encoded within the mitochondrial DNA, known for its significant role in regulating metabolic homeostasis. It primarily interacts with the folate cycle and the AMPK signalling pathway, influencing how cells utilise glucose and fatty acids. Researchers study MOTS-C to investigate its ability to mimic the effects of exercise at a cellular level and its potential to reverse age-related metabolic decline and insulin resistance.
Findings from early-stage clinical trials have reported:
- Enhanced glucose clearance and improved insulin sensitivity observed in experimental models
- Reductions in fat mass and the prevention of high-fat diet-induced obesity reported in-vivo
- Increased levels of endogenous AICAR and activation of the AMPK pathway noted in cellular studies
- Improvements in physical performance and treadmill running capacity observed in ageing research subjects
Researchers study MOTS-C to understand the communication between mitochondria and the nuclear genome. By focusing on its role as a “mitokine,” it serves as a valuable tool for investigating longevity and the prevention of metabolic dysfunction. Its unique mitochondrial origin makes it a focal point for research into how cellular energy production influences systemic health and physical endurance.
Available Formats:
This compound is available in a 9ml premixed spray bottle, providing a stable solution for precise administration in research settings.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
| IDENTIFICATION | |
| Product Name | MOTS-C 10 mg |
| Catalogue Number | RP-MOTSC-01 |
| CAS Number | 1639130-32-7 |
| Molecular Weight (g/mol) | 2174.4 g/mol |
| Molecular Formula | C101H154N30O22 |
| Peptide Sequence | MRWQEMGYIFYPRKLR |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | MOTS-C |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure / sequence |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |
Certificate of Analysis – MOTS-C (99% Purity Verified)
| COMPOUND IDENTIFICATION | |
| Batch / Reference ID | MO100204 |
| Sample Form | White powder in glass vial |
| ANALYTICAL RESULTS | |
| Chemical Purity | 99% (Verified) |
| Measured Content | 10.18 mg (± 0.05 mg) |
| Test Method | HPLC (High-Performance Liquid Chromatography) |
| LABORATORY TESTING INFORMATION | |
| Analysis Period | 03 Mar 2026 – 09 Mar 2026 |
| Laboratory Order # | 100012948 |
| QUALITY ASSURANCE | |
| Quality Testing Standards | All River Peptides products undergo batch-level laboratory analysis to verify compound identity and confirm purity levels. Learn more on our Quality Testing & Purity Verification page. |
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