N-Acetyl Selank – 10mg

N-Acetyl Selank – 10mg

N-Acetyl Selank is an acetylated version of the synthetic heptapeptide Selank, which is an analogue of the naturally occurring tetrapeptide tuftsin. The N-acetyl modification is investigated for its capacity to improve the pharmacokinetic profile of the peptide, specifically focusing on its metabolic stability and penetration into the central nervous system. Researchers study N-Acetyl Selank for its regulatory impact on the GABAergic system and its ability to modulate the metabolism of monoamine neurotransmitters, investigating its role in balancing the emotional and physiological response to stress.

Findings from early-stage clinical trials have reported:

• Improved half-life and enhanced uptake across the blood-brain barrier observed in experimental research.
• Marked stabilization of the serotonergic and dopaminergic systems reported during periods of environmental stress.
• Significant increases in the expression of Brain-Derived Neurotrophic Factor (BDNF) noted in the cerebral cortex.
• Observed modulation of cytokine balance and improved immune-to-brain signaling reported in-vivo.

Researchers utilize N-Acetyl Selank to investigate the intersection of anxiolytic pathways and cognitive stability. By focusing on its ability to act as a regulatory neuropeptide without sedative effects, it serves as a unique tool for studying the biological markers of resilience and neurochemical homeostasis. This makes it an essential compound for research into the management of anxiety-related neurobiology and the preservation of mental performance during high-stress research protocols.

Available Format: 

This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.

Used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use

References

Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission

This study reports measurable changes in GABAergic gene expression in rat frontal cortex tissue following Selank administration. Source Link: Available here

Efficacy of peptide anxiolytic Selank during modeling of withdrawal syndrome in rats with stable alcoholic motivation

This study examines Selank’s effect on stress and anxiety markers during modelled withdrawal, relevant to research on stress-response regulation. Source Link: Available here

A comparison of the anxiolytic effect and tolerability of Selank and phenazepam in the treatment of anxiety disorders in non-psychotic patients

This clinical comparison study evaluates Selank’s anxiolytic profile relative to a benzodiazepine comparator. Source Link: Available here

The influence of Selank on the parameters of the hemostasis system, lipid profile, and blood sugar level in the course of experimental metabolic syndrome

This study investigates Selank’s systemic metabolic effects in an experimental model, relevant to broader physiological research. Source Link: Available here

Effects of the new peptide anxiolytic drug Selank on exploratory activity and emotional state in experimental models

This study assesses behavioural changes associated with Selank administration in preclinical models. Source Link: Available here

The optimizing action of the synthetic peptide Selank on learning and memory processes

This study investigates Selank’s effects on learning and memory consolidation in experimental research models. Source Link: Available here

Selank and regulation of anxiety-related neurochemical pathways

This review discusses Selank’s effects on neurotransmitter systems and neuropeptide signalling pathways in experimental models. Source Link: Available here