Selank (10mg) Spray

Selank  10 mg | Research Compound

Selank is a synthetic heptapeptide analogue of the naturally occurring tetrapeptide tuftsin, modified to include a glyproline sequence for increased stability. It is primarily studied for its anxiolytic (anti-anxiety) properties and its ability to modulate the metabolism of serotonin and other neurotransmitters in the brain. Unlike traditional sedatives, Selank is investigated for its potential to provide regulatory effects on the central nervous system without inducing drowsiness or cognitive impairment.

Findings from early-stage clinical trials have reported:

• Reductions in anxiety-related behaviors and stress markers observed in experimental subjects
  
• Increased expression of Brain-Derived Neurotrophic Factor (BDNF) reported in hippocampal research
  
• Modulation of the GABAergic system and alterations in serotonin metabolism noted in-vivo
  
• Enhanced immune system signaling, specifically relating to cytokine balance, observed in research cohorts
  

Researchers study Selank to investigate the intersection of the nervous and immune systems. Its ability to act as a regulatory agent makes it a valuable tool for exploring neuroprotection, cognitive enhancement, and the biological response to chronic stress. It is a focal point for research into the management of neurochemical imbalances and the preservation of cognitive function during environmental stressors.

Available Formats:
This compound is available in a 9ml premixed spray bottle, providing a stable solution for precise administration in research settings.

Used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use

References

Effects of Selank on gene expression in the nervous system

This study investigated Selank-associated changes in gene expression related to neurotransmission and neuronal adaptation pathways. Source Link: Available here

Peptide Selank enhances the effect of diazepam in reducing anxiety in unpredictable chronic mild stress conditions in rats

This study compares Selank’s anxiolytic activity with a classical benzodiazepine under chronic stress conditions. Source Link: Available here

A comparison of the anxiolytic effect and tolerability of Selank and phenazepam in the treatment of anxiety disorders in non-psychotic patients

This clinical study compares Selank’s anxiolytic effect and tolerability profile to a benzodiazepine comparator in patients with anxiety disorders. Source Link: Available here

Selank, peptide analogue of tuftsin, protects against ethanol-induced memory impairment by regulating BDNF content in the hippocampus and prefrontal cortex in rats

This study examines Selank’s protective effect on memory function via hippocampal and prefrontal BDNF regulation. Source Link: Available here

Efficacy of peptide anxiolytic Selank during modeling of withdrawal syndrome in rats with stable alcoholic motivation

This study investigates Selank’s effect on anxiety-related behaviour during modelled withdrawal in an experimental model. Source Link: Available here

Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission

This paper reports Selank-induced changes in GABAergic gene expression relevant to its proposed anxiolytic mechanism. Source Link: Available here

Selank and regulation of anxiety-related neurochemical pathways

This review discusses Selank’s effects on neurotransmitter systems and neuropeptide signalling pathways in experimental models. Source Link: Available here