PEG-MGF (2mg) — Research Compound
PEG-MGF (Pegylated Mechano Growth Factor) is a splice variant of Insulin-like Growth Factor-1 (IGF-1) that has been pegylated to increase its systemic half-life. It plays a critical role in local muscle repair and growth in response to mechanical stress or injury. By activating muscle-specific stem cells (satellite cells), PEG-MGF is studied for its ability to promote the fusion of new nuclei into existing muscle fibres, facilitating hypertrophy and tissue recovery.
Findings from early-stage clinical trials have reported:
- Significant increases in the activation and proliferation of satellite cells observed in experimental models
- Enhanced rates of muscle tissue regeneration following mechanical trauma reported in-vivo
- Improved protein synthesis markers and muscle fibre diameter increases noted in research studies
- Extended duration of biological activity observed compared to non-pegylated MGF variants
Researchers utilise PEG-MGF to explore the mechanisms of local tissue repair and the regulation of skeletal muscle mass. Its extended half-life allows for the study of sustained growth signalling without the requirement for frequent administration. This makes it a significant compound for research into sarcopenia, muscle wasting diseases, and the biological response to intensive mechanical load.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
| IDENTIFICATION | |
| Product Name | PEG-MGF 2 mg |
| Catalogue Number | RP-PEGMGF-01 |
| CAS Number | 62031-54-5 |
| Molecular Weight (g/mol) | Variable |
| Molecular Formula | PEGylated peptide (variable) |
| Peptide Sequence | MGF peptide with PEG modification |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | PEG-MGF |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with expected PEGylated structure |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C under sterile conditions |


