KPV (10mg) — Research Compound
KPV is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH). It is studied for its potent anti-inflammatory and antimicrobial properties, functioning through the modulation of the NF-κB signaling pathway. Researchers investigate KPV for its ability to reduce pro-inflammatory cytokine production without the systemic effects associated with larger melanocortin peptides. It is a primary focus for studies involving gut health, inflammatory bowel conditions, and dermal wound repair.
Findings from early-stage clinical trials have reported:
- Significant reductions in the expression of pro-inflammatory cytokines such as TNF-α and IL-1β observed in research models
- Improved healing of intestinal mucosal tissue reported in experimental models of colitis
- Reductions in skin inflammation and itching noted in-vivo across various study groups
- Broad-spectrum antimicrobial effects against common pathogens reported in cellular research
Researchers utilize KPV to investigate the regulation of inflammatory responses at the cellular level. Its small molecular size and high stability make it a unique tool for studying localized immune modulation and the biological mechanisms of tissue protection. It is a focal point for research into chronic inflammatory disorders and the development of non-steroidal therapeutic models for autoimmune regulation.
Available Formats:
This compound is available in a 9ml premixed spray bottle, providing a stable solution for precise administration in research settings.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
| IDENTIFICATION | |
| Product Name | KPV 10 mg |
| Catalogue Number | RP-KPV-01 |
| CAS Number | 81734-92-7 |
| Molecular Weight (g/mol) | 386.44 g/mol |
| Molecular Formula | C16H30N4O5 |
| Peptide Sequence | Lys-Pro-Val |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | KPV |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure / sequence |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |
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