PNC-27 (30mg) — Research Compound
PNC-27 is a synthetic peptide derived from the tumor suppressor protein p53 and engineered to selectively interact with cancer cell membranes. In research settings, it is studied for its unique mechanism of targeting malignant cells through membrane disruption, making it a subject of interest in experiments involving malignant cell targeting.
Findings from early-stage clinical trials have reported:
- Selective induction of apoptosis in cancer cell lines observed in-vitro.
- Disruption of cancer cell membrane integrity reported in experimental research cohorts.
- Minimal impact on healthy cell viability noted across comparative studies.
- Observed inhibition of tumor growth markers reported in animal models.
Researchers use PNC-27 to investigate targeted anti-cancer mechanisms and the selective vulnerability of malignant cells, with a focus on understanding how peptide-based interventions may distinguish between cancerous and normal tissues.
Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.
Used solely for in vitro experiments and cannot be:
- Used in clinical trials involving humans
- Administered to humans as part of an experiment or investigation
- Supplied to another party for human investigational use
| IDENTIFICATION | |
| Product Name | PNC-27 30 mg |
| Catalogue Number | RP-PNC27-01 |
| CAS Number | 1159861-00-3 |
| Molecular Weight (g/mol) | ~3164 g/mol |
| Molecular Formula | C151H232N40O37 |
| Peptide Sequence | p53-derived peptide (PNC-27) |
| PHYSICAL AND CHEMICAL PROPERTIES | |
| Active Ingredient | PNC-27 |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| ANALYTICAL AND QUALITY CONTROL | |
| Mass Spectrum | Conforms to specification |
| Structural Confirmation | Consistent with theoretical structure / sequence |
| RESEARCH USE AND SAFETY | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| STORAGE, HANDLING AND STABILITY | |
| Storage Temperature, Opened | -20 °C, minimise freeze–thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions |


