AICAR (50mg) — Research Compound

AICAR (50mg) — Research Compound

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a small molecule that functions as an activator of AMP-activated protein kinase (AMPK), a central regulator of cellular energy balance. In research settings, AICAR is studied for its ability to shift cellular metabolism toward increased fatty acid oxidation and enhanced glucose utilisation, making it a valuable tool for investigating metabolic reprogramming.

Findings from early-stage clinical trials have reported:

• Activation of AMPK and increased fatty acid oxidation observed in skeletal muscle tissue.
• Enhanced glucose uptake and improved insulin sensitivity reported in experimental models.
• Significant increases in endurance capacity noted in research cohorts without exercise training.
• Reductions in fat mass and improved metabolic markers observed in-vivo.

Researchers utilize AICAR to study the mechanisms of energy metabolism and the downstream effects of AMPK signalling on metabolic health. By examining its influence on fuel partitioning and mitochondrial activity, it serves as a specialised tool for investigating how cells adapt to energy stress and how metabolic pathways can be modulated in controlled research environments.

Available Formats:
This compound is available as a vial of lyophilised powder, or can be ordered in a disposable pen, a reusable pen, or a cartridge for an existing reusable pen system.

Used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use