N-Acetyl Semax 10mg Spray

N-Acetyl Semax 10mg Spray

N-Acetyl Semax is a synthetic N-acetylated analogue of Semax, a peptide derived from a fragment of the adrenocorticotropic hormone (ACTH 4-10). The addition of the acetyl group is studied for its ability to enhance the peptide’s stability, increase its resistance to enzymatic breakdown, and improve its ability to cross the blood-brain barrier. Researchers investigate this compound for its potent neurogenic effects, specifically its role in upregulating Brain-Derived Neurotrophic Factor (BDNF) and its potential to modulate the expression of genes involved in vascular health and immune response within the central nervous system..

Findings from early-stage clinical trials have reported:

• Significantly increased duration of biological activity and stability in plasma observed compared to the base peptide.
• Rapid upregulation of BDNF and Nerve Growth Factor (NGF) mRNA expression reported in hippocampal tissues.
• Enhanced cognitive markers related to sustained attention and information processing noted in experimental models.
• Observed protective effects against glutamate-induced excitotoxicity and oxidative stress in neuronal cell cultures.

Researchers study N-Acetyl Semax to explore the limits of neuroprotection and the biological mechanisms of cognitive enhancement. By analyzing its interaction with the melanocortin system and its impact on neuroplasticity, it serves as a specialized tool for investigating the recovery of neurological function after injury. This compound is a primary focus for research into advanced nootropic pathways and the preservation of neuronal integrity under metabolic stress.

Available Formats:
This compound is available in a 9ml premixed spray bottle, providing a stable solution for precise administration in research settings.

Used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use

References

The Peptide Semax Affects the Expression of Genes Related to the Immune and Vascular Systems in Rat Brain Focal Ischemia
This study demonstrated that Semax influences gene expression involved in immune regulation and vascular function, providing important mechanistic insight into Semax research.
Source Link: Available here

Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax)
Researchers investigated the transcriptomic effects of Semax and identified multiple pathways associated with neuroprotection and cellular adaptation.
Source Link: Available here

The Potential of the Peptide Drug Semax and Its Derivative for Neurobiological Research
This publication reviews Semax and its derivatives, including modified forms such as N-Acetyl Semax, within neuroprotective and cognitive research models.
Source Link: Available here

Certificate of Analysis (COA): Available here